CFDE Portal Overview

CFDE Portal Use Cases

The NIH Common Fund (CF) has funded a wide variety of data types and studies that are of interest to clinical and biomedical researchers, however those datasets are hosted on an equally large number of websites, with varying query systems. The Common Fund Data Ecosystem (CFDE) Portal is a unified system for searching across the entire CF portfolio in a single search, and is the first step in addressing the goal of making CF data more Find-able, Accessible, Interoperable and Reusable (FAIR). The wide range of data types, models and formats used by Common Fund Programs are being harmonized using well-defined metadata, common controlled vocabularies using the Crosscut Metadata Model.

By following these tutorials researchers and clinicians will learn to navigate within the CFDE Portal. Users will learn how to use this portal to find datasets from many different CF Programs in a single search to build a cohort, and to save that cohort as a single metadata manifest file. Users will also learn to use the information in the manifest to gather the associated data files from their originating CF data portals. While some discoverable datasets may be public-access, many are likely to be controlled-access. Researchers will be guided to resources for obtaining data access authorization.

Use Case 1: Gathering Blood Cancer Datasets

Est. Time Lesson name Description
10 mins Cohort Selection for Blood Cancer Identify RNA-seq and whole genome sequencing (WGS) datasets in CFDE portal
15 mins Blood Datasets from CF Program Portals Access identified cohort in individual CF data portals

Use Case 2: Compiling Datasets of Movement-Related Disorders

Est. Time Lesson name Description
10 mins Multi-omics Data Discovery for Movement-Related Disorders Identify multiomics datasets
10 mins Movement Disorders Datasets in CF Program Portals Access identified datasets in individual CF data portals

Learning Objectives

In this tutorial you will learn:

  • how to build cohorts for Blood Cancer

  • how to build cohorts for Movement-Related Disorders

  • Access to MacOS, Windows or Linux
  • Access to the internet and a web browser
  • Basic knowledge of mammalian biology

Last update: October 15, 2020